Nir2 expression modulates cell morphology
The effect of Nir2 on cell morphology was assessed upon Nir2 overexpression and downregulation. Its downregulation induced epithelial-like phenotype, while its upraegulation mesenchymal, with reduced […]
Epithelial-Mesenchymal Transition
Nir2 regulates cell migration and invasion
Professor Sima Lev team found that the phosphatidylinositol (PI)-transfer protein Nir2 positively regulates the migration and invasion of breast cancer cells using wound assays and […]
Epithelial-Mesenchymal Transition: EMT
EMT a crucial developmental process implicated in organ development, tissue repair, and organ fibrosis, plays a major role in cancer progression, invasion, and metastasis. EMT […]