Nir2 expression modulates cell morphology

Lab of Sima Lev

The effect of Nir2 on cell morphology was assessed upon Nir2 overexpression and downregulation. Its downregulation induced epithelial-like phenotype, while its upraegulation mesenchymal, with reduced cell-cell contacts mediated by tight junction (Zo-1) and adherens junctions (E-cadherin).

Nir2 expression modulates cell morphology
Nir2 expression modulates cell morphology by Sima Lev’s lab team

Be the first to comment

Leave a Reply

Your email address will not be published.


*